Glaxosmithkline, Bristol-Myers Squibb, and Aids in Africa

†¢ Case – 2 Marks-20In 2004, the United Nations estimated that the previous year 5 million more people around the world hadcontracted the AIDS virus, 3 million had died, and a total of 40 million people were living with theinfection. Seventy percent, or about 28 million of these, lived in sub – Saharan Africa, where the epidemicwas at its worst. Sub – Saharan Africa consists of the 48 countries and 643 million people who residesouth of the Saharan desert. In 16 of these countries, 10 percent are infected with the virus, in 6 othernation, 20 percent are infected. The UN predicted that in these 6 nations two – thirds of all 15 – year oldswould eventually die of AIDS and in those where 10 percent were infected, half of all 15 – year –†¦show more content†¦In1987, Burroughs Wellcome (now part of GlaxoSmithKline) developed AZT, the first FDA-approvedantiretroviral, that is, a drug that attacks the HIV virus itself. When wellc ome priced AZT at $10,000 for ayear’s supply, it was accused of price gouging, forcing a price reducing of 20 percent the following year. In1991, Bristol- Myers Squibb developed didanosine, a new class of antiretroviral drug called nucleosidereverse transcriptase inhibitors. In 1995, Roche developed saquinavir, a third new class of antiretroviraldrug called a protease inhibitor, and the following year Roxane Laboratories announced nevirapine,another new class of antiretrovirals called nonnucleoside reverse transcriptase inhibitors . By the middle1990s, drug companies had developed four distinct classes of antiretrovirals, as several drugs thatattacked the opportunistic diseases that afflict AIDS patients. In 1996, Dr. David Ho was honored for his discovery that by taking a combination- a â€Å"cocktail†- ofthree of than four classes of antiretroviral drags, it is possible to kill off virtually all of than HIV virus in apatient’s body, allowing the immune system to recover, and thereby effectively bringing the disease intoremission. Costing upwards of $20,000 a year (the medicines had to be taken for the rest of the patient’slife), the new drug treatment enabled AIDS patients to once again live normal, healthy lives. By 1998, thelarge drug companies wouldShow MoreRelatedCompany Ethics and Moral1176 Words   |  5 Pagesdisease, diabetes, hepatitis, Parkinson’s, HIV/AIDS and some cancers (Dowdall, 2014). Without several of these drugs that are provided by these companies, many people would not live healthier longer lives. â€Å"Malaria, a mosquito-borne parasitic disease, kills hundreds of thousands of people a year, mainly babies in the poorest parts of sub-Saharan Africa, and scientists say an effective vaccine is key to attempts to eradicate it† (Moorthy, 2013). GlaxoSmithKline, a British drug maker has created the worldsRead MorePharma Industry Analysis1714 Words   |  7 PagesGood health is an important personal and social requirement and the unique role pharmaceutical firms play in meeting society’s need for popular wellbeing cannot be underestimated. In recent times, the impact of various global epidemics e.g. SARS, AIDS etc has also attracted popular and media attention to the industry. The effect of the intense media and political attention has resulted in increasing industry efforts to create and maintain good government-industry-society communications. TechnologicalRead MorePfizer Tested A New Antibiotic1483 Words   |  6 Pagestiming of antiretroviral treatment for HIV positive people is taking place in the African countries of Morocco, Mali, Nigeria, South Africa, and Uganda (â€Å"Strategic Timing†). The Strategic Timing of Antiretrovial Treatment (START) study is currently sponsored by the University of Minnesota and has twenty-one collaborators including GlaxoSmithKline, Bristol-Myers Squibb and Merck. The study s objective is to assess the mortality rate of HIV patients over the course of four years. Numerous antiretroviralRead MoreEthical Justification For Providing Life Saving Medicines2109 Words   |  9 Pagesshareholders of the company, especially in recouping the money that has been spent on the research. If a company does patent its HIV/AIDS drug then they protect it from being common knowledge and avoid losing an edge over other companies, not to mention the millions or billions in profits. Today, approxima tely 35 million people in the world are currently living with the HIV/AIDS disease (13), which leads us to the question: Should pharmaceutical companies be forced to make drug advancements public knowledgeRead MoreGsk Marketing Planning4419 Words   |  18 PagesGSK Marketing Planning | March 31 2013 | Calvin Cheung, Hussain Al Katib, Manpreet Budwal, Sandra Okechukwu | SOSTAC Review based on GlaxoSmithKline | Content Table of Contents 1.0 Introduction2 2.0 Situation Analysis3 2.1 PESTEL Analysis3 2.2 SWOT Analysis4 2.3 Boston Matrix5 2.4 Porter’s Five Forces Analysis6 3.0 Objectives8 4.0 Strategy9 4.1 Product9 4.2 Price9 4.3 Promotion9 4.4 Place10 4.5 Person10 4.6 Process10 4.7 Physical Evidence10 5.0 Tactics11 6.0 Action Plan12 Read MoreHistory and Analysis of the Pharmaceutical Industry4211 Words   |  17 PagesGood health is an important personal and social requirement and the unique role pharmaceutical firms play in meeting society’s need for popular wellbeing cannot be underestimated. In recent times, the impact of various global epidemics e.g. SARS, AIDS etc has also attracted popular and media attention to the industry. The effect of the intense media and political attention has resulted in increasing industry efforts to create and maintain good government-industry-society communications. TechnologicalRead MoreGlaxosmithkline18561 Words   |  75 PagesGlaxoSmithKline company profile Francis Weyzig Amsterdam, October 2004 Summary Business description GlaxoSmithKline (GSK) is one of the world’s largest research-based pharmaceutical corporations that discovers, develops, manufactures and markets branded human health products. Headquarters: UK, with additional operational headquarters in the USA Global presence: about 160 countries Primary markets: USA, France, Germany, UK, Italy and Japan Employees: approximately 103,000 GSK key figuresRead MoreMergers Acquisitions in Pharma Industry21425 Words   |  86 PagesPROJECT REPORT ON A Successful International Merger in India: GlaxoSmithKline pharmaceutical industry Table of Contents: Declaration Abstract Part I –Introduction Research Objective and justifications Report Outline Part-II Industry DescriptionRead MoreProblems Facing the Pharmaceutical Industry and Approaches to Ensure Long Term Viability14741 Words   |  59 Pagesconsumer 3 products, healthcare services, medical devices and medical diagnostics. Yet other companies have taken the path of focusing on the Emerging Markets that are in some ways considered largely untapped potential like AstraZeneca and GlaxoSmithKline s focus on China and India respectively. These are examples of changes that point to the fact that many Pharma companies do not see the current situation as a temporary setback. Many are making the decision to work with former competitors (EliRead MoreGsk Annual Report 2010135604 Words   |  543 PagesDo more, feel better, live longer GlaxoSmithKline Annual Report 2010 Contents Business review P08–P57 Governance and remuneration P58–P101 Financial statements P102–P191 Shareholder information P192–P212 Business review 2010 Performance overview Research and development Pipeline summary Products, competition and intellectual property Regulation Manufacturing and supply World market GSK sales performance Segment reviews Responsible business Financial review 2010 Financial position and resources

History of Chess Free Essays

The precursors of chess originated in India during the Gupta Empire,[2][3][4][5] where its early form in the 6th century was known as chatura? ga, which translates as â€Å"four divisions (of the military)†: infantry, cavalry, elephantry, and chariotry, represented by the pieces that would evolve into the modern pawn, knight, bishop, and rook, respectively. [6] Chess was introduced to Persia from India and became a part of the princely or courtly education of Persian nobility. 7] In Sassanid Persia around 600 the name became chatrang, which subsequently evolved to shatranj, due to Arab Muslim’s lack of ch and ng native sounds,[8] and the rules were developed further. We will write a custom essay sample on History of Chess or any similar topic only for you Order Now Players started calling â€Å"Shah! † (Persian for â€Å"King! â€Å") when attacking the opponent’s king, and â€Å"Shah Mat! † (Persian for â€Å"the king is helpless† – see checkmate) when the king was attacked and could not escape from attack. These exclamations persisted in chess as it traveled to other lands. The game was taken up by the Muslim world after the Islamic conquest of Persia, with the pieces largely keeping their Persian names. The Moors of North Africa rendered Persian â€Å"shatranj† as sha? erej, which gave rise to the Spanish acedrex, axedrez and ajedrez; in Portuguese it became xadrez, and in Greek zatrikion, but in the rest of Europe it was replaced by versions of the Persian shah (â€Å"king†). Thus, the game came to be called ludus scacchorum or scacc(h)i in Latin, scacchi in Italian, escacs in Catalan, echecs in French (Old French eschecs); schaken in Dutch, Schach in German, szachy in Polish, sahs in Latvian, skak in Danish, sjakk in Norwegian, schack in Swedish, sakki in Finnish, sah in South Slavic languages, sakk in Hungarian and sah in Romanian; there are two theories about why this change happened: 1. From the exclamation â€Å"check† or â€Å"checkmate† as it was pronounced in various languages. 2. From the first chessmen known of in Western Europe (except Iberia and Greece) being ornamental chess kings brought in as curios by Muslim traders. The Mongols call the game shatar, and in Ethiopia it is called senterej, both evidently derived from shatranj. Chess spread directly from the Middle East to Russia, where chess became known as (shakhmaty, treated as a plural). The game reached Western Europe and Russia by at least three routes, the earliest being in the 9th century. By the year 1000 it had spread throughout Europe. [9] Introduced into the Iberian Peninsula by the Moors in the 10th century, it was described in a famous 13th century manuscript covering shatranj, backgammon and dice named the Libro de los juegos. Chess spread throughout the world and many variants of the game soon began taking shape. [10] Buddhist pilgrims, Silk Road traders and others carried it to the Far East where it was transformed and assimilated into a game often played on the intersection of the lines of the board rather than within the squares. [10][11] Chaturanga reached Europe through Persia, the Byzantine empire and the expanding Arabian empire. 12] Muslims carried chess to North Africa, Sicily, and Iberia by the 10th century. [10] The game was developed extensively in Europe, and by the late 15th century, it had survived a series of prohibitions and Christian Church sanctions to almost take the shape of the modern game. [13] Modern history saw reliable reference works,[14] competitive chess tournaments[15] and exciting new variants which added to th e game’s popularity,[15] further bolstered by reliable timing mechanisms (first introduced in 1861), effective rules[15] and charismatic players. [16] How to cite History of Chess, Essay examples

Introduction Essays - Exercise Physiology, Anabolic Steroids

Introduction Steroids are hormonal substances, naturally produced in the body by the adrenal glands above the kidney and by reproductive organs. There are many different types of steroids and they all have different effects on the body. Some types of steroids have been found to help destroy some types of cancer cells, and can make more effective. This fact sheet describes steroids, how they are given and some of the side effects that may occur. Common types of steroids that are used in cancer treatment are: hydrocortisone, dexamethasone, methylprednisolone and prednisolone. Dexamethasone is also used in low doses as an anti-sickness drug. In this case it is usually only given for short periods of time and the side effects described in this fact sheet will not necessarily apply. It is important to remember that each persons reaction to any drug is unique and some people have very few side effects. The effects will also vary according to the dose of the steroid that you are having and may be different if you are also receiving other drugs. We have outlined the commonest and less common side effects, so you can be aware of them if they occur. However, we have not included those which are very rare and therefore extremely unlikely to affect you. If you do notice any effects which you think may be due to the drug, but which are not listed in the fact sheet, please discuss these with your doctor or nurse. You will have regular appointments with your doctor to monitor the effect of the steroids. This fact sheet should help you to discuss any queries about your treatment and its side effects with your doctor or chemotherapy nurse. They can help and advise you. What steroids look like A clear fluid after being dissolved from powder, or tablets. The color and dose of the tablets depends on the type of steroid used. Soluble tablets are available for people who have difficulty in swallowing. How they are given The fluid is given by injection into a muscle (intra muscular) or vein (intravenous). If the steroids are given intravenously a small tube (cannula) will be inserted into the vein, and the steroids are given either as a quick injection through the tube or as a drip which takes about 30 minutes. They may be given through a central line which is inserted under the skin into a large vein near the collarbone. The tablets are swallowed with plenty of water. They may need to be taken at set times each day or may be given in short courses. Possible side effects Irritation of the stomach lining. Steroids can increase the production of stomach acid and lower the production of protective stomach mucus. This can irritate the lining of the stomach and may cause or aggravate a stomach ulcer. To reduce this side effect the tablets should be taken with meals or milk. Tell your doctor if you have indigestion, stomach pains or abdominal discomfort. The levels of sugar in your blood may change temporarily. This may happen if you have high-dose or long-term treatment. While you are having your steroid therapy your blood sugar levels will be checked regularly by blood tests. You may be asked to test your urine for sugar. You will be shown how to do this. Tell your doctor if you get very thirsty or if you are passing more urine than usual. Fluid retention due to changed salt and water balance. You may notice that your ankles and/or fingers swell. Some people have a bloated feeling in the abdomen. This is usually only a problem with long-term treatment. Increased appetite. You may notice that you feel than usual while taking steroids, and this can make you want to eat more than usual. If you are concerned about weight gain speak to your doctor or contact CancerBACUPs information service. Increased chance of infection and delayed healing of injuries. This happens mainly with high-dose or long-term treatment. Tell your doctor if you notice signs of infection (inflammation, redness, soreness or a temperature) or if cuts take longer than usual to heal. It is important to maintain good personal hygiene to prevent infection. Menstrual changes.

Poetry Analysis Essay the Relationship between Form and Content

Poetry Analysis Essay the Relationship between Form and Content Poetry Analysis Essay: the Relationship between Form and Content If you have been assigned with the task of writing a poetry analysis essay you may be wondering where to begin and what details you should cover when discussing a particular piece. Here are some tips that you can use to make this task more manageable and, in the course of your writing, gain a deeper understanding of the particular poem you are discussing. Many students will analyze a poem using a few common factors. These include: The language that is used in the piece itself including the choice of specific words by the poet; Specific imagery that the poet chose to include in the poem; The social factors that may have affected the poet when writing a specific poem. This is the content part here and all of these factors are very important for you to look at when you are writing a poetry analysis essay and all three of them look at the same element: the actual words that the poet used. However, when you limit yourself to examining the language itself, there is a lot of meaning and nuance that you are potentially missing out. What Poetry Is about? On the surface, it may appear as though a poet is trying to convey one meaning. After spending time digging down deeper into the poem and looking at it more closely it may become more evident that the poet had an entirely different thought or meaning in mind when he or she wrote a particular piece of a verse. When you look at the content and form separately, you have two different aspects that draw varied pictures. But when you analyze these two factors together, they can illustrate a very different story because a particular form can strengthen or weaken the utterance of an author and that must be taken into account. With that in mind, while looking into the form you need to pay attention to: How the verses are broken up; What the rhyming structure is; Whether the poet uses the traditional iambic pentameter system for their poem or a different metric system; Whether particular sections are repeated for effect or to convey a message. Each of these parts can affect a poem’s meaning and discounting them may lead to the fact that you miss what the writer is trying to say. For example, if a poet continues to repeat certain structures in a particular piece, it may mean that the theme expressed in the echo is much more important than you may initially believe. How Do You Break down the Poem and Make It Easier to Analyze? Breaking down the poem can actually make it easier to analyze. It is helpful to first look at the poet themselves. Finding out about their life and the era in which they lived can give you some valuable insight that may help you accurately analyze what they have written. Breaking the poem down stanza by stanza and looking at the form of each verse can help you look for the clues and information that you will want to include in your essay. For example, you can look at important elements such as: The tone of each verse. Does it change throughout the course of the poem? Does this tonal change contain important information about the poem? What is the structure of the stanza itself? Does it stay consistent throughout or is a particular verse written in a different structure? Is that differing structure repeated throughout the piece or is it simply an anomaly meant to highlight a particular image or idea? Which Aspects of the Poems Form Should You Focus on? If you are writing an essay and want to discuss the form of a piece you may be unsure of how to work these discussion points into the body of your essay. It doesn’t have to be hard if you keep a few important steps in mind. The first is to figure out what the thesis or basic idea behind your essay will be. This can help you by narrowing down specific stylistic points to focus on. Sometimes the style or form of a poem can be complicated and trying to write about every aspect of it may be overwhelming and may even seem confusing and disorganized for the reader. By narrowing down your commentary to specific aspects of a poem’s style you may find it easier to get your point across and lead your reader to the conclusion you want them to make. Once you start looking at a particular poem in depth you will begin to see how a stylistic point can become more or less important and this will help you determine whether it has a place in your essay or not. At you can buy an essay online which will be 100% custom written from scratch. All you need is to place your order  at our site!

How to Keep a Reading Log or Book Journal

How to Keep a Reading Log or Book Journal A reading log or book journal is a great place to note your reactions to what youre reading. Writing down your responses will allow you to discover  how you feel about the characters. Youll also gain insight into the theme and plot, and it may enable you to deepen your overall enjoyment of reading literature. You can keep a hand-written reading journal using a notebook and a pen, or you can keep an electronic one on a computer or tablet.   Below are a few idea starters to get your creative juices flowing. Feel free to build your list of questions. You may find yourself starting a life-long habit of keeping a reading log or book journal. How to Keep a Reading Journal First and foremost, start recording your immediate reactions to the text as you read it. Begin with  the opening chapter of the book. How do your impressions change (if they do) after reading half the book? Do you feel any differently after finishing the book? Would you read the book again? What emotions did the book invoke: laughter, tears, smiles, anger? Or did the book seem boring and meaningless you? If so, why? Record some of your reactions. Sometimes books touch you, reminding you of your own life as part of the larger human experience. Are there connections between the text and your own experience? Or does the book remind you of an event (or events) that happened to someone you know? Does the book remind you of what happened in another book youve read? Write about the characters, considering these questions: Which one is your favorite? What do you like about that character?Are there any personality traits that youd like to have?Conversely, is there a character you dislike? Why?What traits could you change about that character? Do you think that any of the characters represent  real  people?Does anything about a particular character seem to be related to the authors true personality?Do any of the characters represent general personality types? Is the author commenting on these types of people? Consider the Names Used in the Book If you were the author, would you have changed the name of a character or altered the location of a scene?What does the name mean to you?Do you have a negative connotation associated with the name (or the place)?What would you name the character instead?What would you use as a setting? Do You Have More Questions Than Answers? Upon finishing the book, does it leave you with questions? What are they?Would you like to direct your questions at a particular character?What questions would you like to ask the author of the book?Are they questions that you may be able to answer by reading more about the authors life and works?   Being Confused is Okay Are you confused about what happened (or didnt happen) in the book?What events or characters do you not understand?Does the use of language in the book confuse you?How did your confusion affect how you liked the book?Is there anything that the author could have done to clarify or answer any questions you were left with? Taking Notes Is there an idea in the book that makes you stop and think or prompts questions? Identify the idea and explain your responses. What are your favorite lines or quotes? Copy them into your journal and explain why these passages caught your attention.   How have you changed after reading the book? What did you learn that you never knew before? Who else should read this book? Should anyone  be discouraged from reading this book? Why? Would you recommend the book to a friend or  classmate? Would you like to read more books by this author? Have you already read other books by the author? Why or why not? What about other similar  authors  or authors of the same period? Write a summary or review of the book. What happened? What didnt happen? Capture what stands out about the book for you (or what doesnt). Tips on Keeping a Book Log Keeping a reading log or book journal can work well for poetry, plays, and other works of literature as well, though you may want to adjust the questions accordingly.  Consider reading the diaries, logs, or journals that great writers have kept about their reading experiences. You may even be able to compare notes. How do your reactions to books compare to the thoughts of famous writers?

Homeless Essay Example | Topics and Well Written Essays - 250 words

Homeless - Essay Example These provisions may pertain to clothing, food, water and others. It is the place with a four corner framework made suitable for subsistence and constant dwelling. That’s why an individual can be considered homeless in the absence of these fundamental physical features. As a result, such person is moving from place to place. On the other side, being homeless can also mean that the person has a house but he or she does not have a company in times of exigencies and loneliness. In other words, the individual is just living alone. Moreover, it is commonly accepted that a home is not a home in the absence of a family residing therein. Therefore, having a family is recognizing the fact that humans need the company of others to live and reproduce. This is the basis of the difference between a residence and a home. A residence is more of the physical existence while a home is more of the social existence. Accordingly, there are two essential elements that can be inferred from the word homeless: the individual self and the absence of a home or a residence. Thus, a home has a dual purpose: physical and social

Essay of the Korean film my wife is a gangster(2001)

Of the Korean film my wife is a gangster(2001) - Essay Example not only revive the Korean cinema with the predominant feature of gangster movies but also with the concern of gender representations which was something that the Korean movies hadn’t seen before. Gangster movies have been a common aspect of the Korean films but the Korean film industry has seen a significant change since the release of mega-hit movies such as My Wife is a Gangster and My Sassy Girl. These films had changed the perception of gangster movies in the Korean culture as they involved an improved representation of women in the society (Choi, 2010). The film showed a female gangster who is looking for a husband to fulfill the wish of her dying sister. The woman simply ordered her supervisors to look for an appropriate man and when they found one, he is seen teaching her how to behave like an appropriate woman. The female gangster, Eun-jin is usually seen suppressing her husband and avoiding to do the homely chores that she is expected to do as a wife. She gets pregnant and at the same times gets in deeper trouble with her doings as a gangster. Traditionally, the representation of women and gangster movies in the Korean film industry were two different perceptions. Women in Korea were often depicted under the patriarchal conventions and were seen in movies such as romance or comedy. Even though My Wife is a Gangster saw women in a tough image, the overall representation of women was still seen from the male perspective not only in Korea but in most of the Asian countries. The Korean gangster films including women in tough roles did not tend to detect the misrepresentation of women and these films commonly concealed the misrepresentations of women. Many of the common spectators are unconsciously filled with the movie’s hidden meanings and their ideologies (Choi, 2010). The critical thinking on the Korean gangster movies until My Wife is a Gangster was related to suited men involved in gangster wars that had become the highest profiting trend for